I formerly had a .222 Rem. in a 788. In spite of the chamber being a bit on the large side of tolerances, with fireformed cases it was an accurate, easy to load for cartridge. A heck of a lot better than the Hornet I had before.
But, when I used it for coyote hunting, I felt it was lacking. This was not calling, where the shots would likely be at a stationary target, but driving sections, pushing them to other hunters. One coyote I shot at was running across a couple of plowed fields and I fired a total of 8 shots at it, but could not see where one bullet struck the ground. The shots were between 200 and 250 yards away and I never saw a bullet strike in the field, no dust .... no dirt fly. After that experience I went to a .243 Win shooting a 70 grain Nosler BT. When I miss, I can see dirt fly and make a correction.
For a calling rifle, the .222 Rem. will probably work fine, but if you are driving them, or dogging them, as are the common practice in this area, it leaves much to be desired. Many of the shots are relatively long ranged, and the hunters prefer to use an AR for multiple shots or something in a bolt gun like a .243 Win, or an even flatter shooting cartridge like a .25/06 or 6mm X .284.