I shoot a 257ai built on a model 721 remington. Not shooting anything as light as a 75, but between 87 hornady, 100 nosler bt and a few others in that range. use imr 4350, rl 19 and tried h380. the 87 hornady shot best with the rl 19, the 100 bt was best with the imr 4350. my barrel does not do well with anything heavier than the 100g. As far as loading for it, my fire form loads do pretty well, and are not wasted. Everything else is the same as loading anything else. Good luck with it, this is my second one, and a keeper.
Barry