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I have probably loaded more IMR4350 in more cartridges than anything else. It works well in a lot of them. I still find R-22 and 4831sc better in the 270. As some have mentioned, they seem to do best when pushed to max or near max and that's why I handload. I want the fastest, most accurate load possible. If you are happy with your current load, stick with it. If it ain't broke don't fix it. But sometimes tinkerin' is fun too.......2MG