My method, right, wrong, or indifferent is: If you have a factory round that is accurate, that is a VERY good starting point. You know the bullet you want to shoot. I also measure the OAL, of the factory round (to the ogive is better). You know the kind of brass that the factory is using. You have the suggestion of Winchester primer (that may vary, but a good starting point).
If you could chronograph the factory load would be best, but your ballistic program may be good enough. I would check loading data and see which powders will get you close to the factory. H4350 may, or may not be the best powder. I would start low, and work up with powder charges, checking accuracy and speed. As you know, most factories use their own powder, so you may not reach factory speeds. But, I bet you will be able to come up with a load that has the accuracy you want. A chronograph is a valuable tool in this process if you have one, or access to one! Good luck...keep us posted with your progress.