Toby10:
The info given here on MPBR is all OK, the Lyman #47 and #48 manuals (older manuals) both have an excellent explanation of it. Point is, when you see a smaller target in the field, you cannot re-adjust the current MPBR established for deer to fit a coyote...SO....you set it to start with for your most likely game pursued with that weapon...
For your 22/250, just sight it in to be dead-on at 200 yards +/-, and know the trajectoy of that sight in, both at ranges shorter than 200 and ranges longer than 200 yards
The Nosler #4 manual has a complete ballistics table for all caliber bullets [perhaps not the 204 Ruger or 17, but the rest) at all velocities and ranges from 0-600 yards.
With the Nosler #4 or similar manual's table, you can figure out a chart with the drop for your particular bullets used and the [estimated] velocities at 50, 100, 200,300 yards, and for wind drift caused by of 10,15,20miles per hour. Your chart will not be super spot on, but pretty darn close; tape it to your rifle as a reference piece, and you will eventually memorize it.
Good hunting.
