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I use 50gr vvax.  I shot my bobcat at 381yds and the exit was about quarter sized.  You can see a pick of the exit side in my photo hosting.  They both will do alot of damage inside 100yds.  If you want to keep pelt damage down  get some 60gr barnes bullets or some partitions.  The harder you push they the more violent they will expand.  I load my 50s to about 3400fps.