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I also like the 52 gr. HP in the 22-250 for coyote. The T-3 loves Sierra HPBT match #1410. Shot broadside through the ribs leaves a managable 1" exit hole. Enough penetration to anchor if shot through leg bones and never a splash like some ballistic tip bullets. I try to hit them below the midline so the hole (that l sew) is on the belly side of pelt.