Hi,
I think there has been nearly as much said about if a barrell should be shot in and if so how, as there has been in more recent years about the Bible.
From one person who believes in barrell break-in:
Shoot once and clean: repeat five times.
Shoot three times and clean: repeat five times.
Shoot five times and clean: repeat five times.
A major consideration is getting it CLEAN. One tip: test to see if it is clean by soaking a patch, running it through the bore, let the solution do its job and then see if it picks up residue.
Do some reading on the subject of cleaning and barrell break-in.
Have fun