I've never timed it on by 550B. I only use mine for pistol rounds but I'd guess maybe 20 minutes tops depending on whether you have to completely change and adjust powder and primer feeds, and assuming your dies are still set from the time before. It's a piece of cake, however I'm slow and don't think I've ever cranked out more than 200 or 300 in an hour, but that's because I like to test/measure every few loads for the proper powder level, use a case gauge periodically on the load shells, and I'm always getting distractions. There's no reason to think rifle rounds would take any longer to set up.