Like 2much, I never found Nosler bullets to my liking with the exception of their Partition bullets. I run the Hornady Interlock 139gr. behind H414 powder and find it a very accurate combo in my Kimber. And I under stated that too.
I would "maybe" have to rethink my bullet selections if I lived out West and regularly shot game past 400yds., but I don't and I won't shoot that far. Therefore, I find that the ol' standby bullets which are generally scoffed at work perfectly for me and others I know who hand load. From 30-06 to 270 to 7-08 to 7mm mag. to 243 to 280 and to 300 Win. mag. our bullet of choice is either Rem. core lokt or Hornady Interlock sp flatbase. The game is Whitetail Deer and between all of us the average is 30 plus Deer harvested every season.
So for what its worth, that's our experience.