I see the main advantage to a sequence as being eyes on the horizon and not the remote. You can always mute the call and change sounds, you don't have to carry on with the sequence. I have a coyote sequence I made, it's rabbit distress, mute for 4 mins, repeat. volume goes from 25% to 50% over the course of 15 mins or so and then tapers back down. You don't need to make one so complex it or off the wall that it might be a hindrance in the field
I find when I use the remote I am very eager to change sounds and periods of silence always are shorter than should be. With a sequence I am more relaxed and ready to kill
my .02
