Over the last 25 plus years I've used magnum primers in everything I shoot that takes a large rifle primer. Started out just to cut costs stocking so many primers. Use them for the 22-250, 220 Swift, 243, 280 Remington, 06, and the 308 along with the 7mm Rem mag, 7mm STW, 300 win mag, 300 Rem Ultra mag, 8mm Rem mag and the 338 win mag.
Never had a problem, but do work all loads up when you change any component.
