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I shot a 110 grain bullet from my 300 Win mag, but not at coyotes yet. They are the most accurate round I have ever put through the gun with three shoot groups in the sub .5" range. They Chrono at just a tad under 3700 fps. But I shoot Hornady SP not V-max. I loaded up some 110 grainers for my friends savage 10FP and it really liked near 48g. of Win 748, just about 3300 fps and MOA 5 shoot groups from that gun.