Personally I'd have what I have threaded.
Pick a can, highest quality you can afford, and go for broke.
There are some cans that in the .22 CF range that actually are 6mm capable. Although, those I would definitely use a alignment rod if shooting 6mm bore sized host. If I wanted to use just 1 can. Which I personally don't do, and would advise to go .30 caliber as insurance, to prevent baffle strike. I like to use QD mounts, which also drives my opinion to what I mentioned.
Direct thread is "usually" more concentric to the bore, but not always. Either method can be off.
Which is best? The one you pick, although others will argue and have opinions. But fact is the one that works for you is usually great. My hunting buddy only does direct thread, while I use QD mounts. Both systems work. I just simply prefer the quick change ability with the QD method. Although one can I have is direct thread only. (here I'm referring to Centerfire cans only, the rimfires can are all direct thread.)
Omega 300 has been a work horse for me. The OCL plutonium series (long version) have treated me well, and replaced the Omega on the .22 Centerfire host's.
The AB series are extremely interesting to me, don't have one in the stable. (doesn't mean I would not like to obtain one later). From what I can see that offering is worth while while I can't tout it from personal experience. The reflex ability is desirable (AB Raptor10, usually around 1,000.00, the 8 is a bit more affordable), although the OCL plutonium can be done as a reflex as well, which honestly after purchasing the items from OCL is not a true cost saving over the Raptor.
Suppressors are like tator chips ya just can't have one and lead to a addiction of sorts.