I have and shoot a 1917 Eddystone (made by Remington). It is one that is a real fine shooting piece. I have hand loaded mine with both the IMR 4064, and IMR 4350 and the powder is not the trouble, with 150 grain i used on whitetail, of with 165 grain or with 180 grain. All worked well in grouping my shots.
I think i had in IMR 4350, 58 grains for 150grain bullet, 56 grains for 165 grain bullet, and 54 grains for 180 grain bullet. all with regular large rifle primers, not magnumns. I never did the 220 grain round nose.
I wish you well. Good shooting. It's a fine gun.