I,ve shot lots of em out of both .223 and 22-250. Very accurate from most guns, accurate enough for most hunting applications anyway. They work very effectively on coyotes, but you will probably get more exit wounds than what you would see with ballistic tips, unless you are trying to save hides this really isn't much concern. I lived in your area long enough to know most of the yotes you encounter aren't going to take much of a price drop from an exit wound, they aren't worth much to bigin with. As for deer, i have little experience with the .22 caliber bullets, but i did loan a 223 to a friend and his son shot his first two deer with these bullets without any problems, entry right behind shoulder and bullet stopped against hide on opposite side, one was at 186yds. One fell right were it was shot, the other went about 30 yds, just have to be very selective with shot placement, as you should be with any caliber/bullet.