Greetings,
I live in Manitoba so I'm not sure if the rabbits in your area are subject to any particular problems that would make them unfit for consumption. However, what has served me well, as a general rule of thumb, is to look at the liver and other internal organs. If everything looks healthy, things should be OK. If there are white spots on the liver, then there's probably somthing wrong with that critter and you should avoid it.
Another thing to note, even before you shoot if you can, is to observe it the animal is behaving normaly. If it looks sick, has sores on it or whatever, then you may want to avoid that animal.
One last thing, be sure to wash your hands thoroughly after cleaning your critters!
BTW, I just happened to introduce a jackrabbit to a 3200fps 55grn V-max from my .223 last Sunday... he was big, healthy... and tasty /ubbthreads/images/graemlins/laugh.gif