Full power for sure! That's why you buy the full power. If at 14, 16, 18 or 20+ power you are a little off, you can easily fine tune and git'r dialed in. Then in normal hunting situations go with the power that provides YOU with the field of view your the situation dictates: Under 100 yards go low: (2.5 to say 5) 150 yds? 6,7,8,9...out farther? You make the call. Is the target on a steady bearing, but moving... or crossing or stationary? All the factors have to be considered. Time is also a factor...if it's a running coyote, full power really isn't an option under most circumstances. Unless you are a super shot. I usually leave my scope at 6 when hunting here in the desert. If I get back-doored...I go to plan B...sidearm.