My blued 4 5/8" SBH likes:
240-250gr cast + 5grs Bullseye
240-250gr cast + 10grs Unique
300gr cast + 9.5grs AA #2
310gr WFNGC + 21.0grs H110 - this one's bad news
310gr WFNCG + 9.5grs Unique
240 XTP + 19.0grs 2400
240 XTP + 24.0grs H110
300gr Sierra + 15grs 2400
My factory sights work with all loads.
My barrel has been fire lapped and I get no leading on any of those loads. All shoot better than I can.