I've been using the 140 tsx in a 270 wby since they came out. Outstanding bullet, shot two groups at 540 yards that measured 4.5", off a bipod while practicing for deer season last fall. That rifle is pure death.
I also worked up a load for a friends 7 mag with the 120 ttsx, they averaged 1.5" at 200 yards, that's as far as I shot it. He shot his deer with those at 400 yds this fall.
I currently have some 80 ttsx for my 25 wssm ar to try when the weather is better. I might wait till this summer to work with them.
they are expensive, and it will take a box at least to find a good load, because seating depth is very critical. But once you do they are very consistant and deadly on game.