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It really depends on your hunting conditions.  Here on the east coast, you tend to hunt hogs in the think brush and close-up shots are the norm. I personally like the 12 gauge slug in thick conditions, but if you really want a thrill of a life time use a bow or better yet a spear. Any caliber will really do. It all depends on shot placement. As long as you do your part, the bullet will do the rest. I even have a video tape of someone harvesting two hogs one with a blow gun and the other with a bowie knife. Good luck!