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Try 1/4" high at 50 yrds. It should get you around 1 1/4" high at 100 yards. This is assuming you are using a high velocity .22 centerfire or the like. It seems to also work well for my .243. There is really too much variance to say exactly what your 100 yard height will be exactly, but I have always started with the 1/4" at 50 and it has always worked well.