Last year my .223 was zeroed @ 200 yds with 55gr Black hills. 100 yd impact was just shy of 2" high. 50 yd impact was right on. Covers the bases pretty well, IMHO. This year I'll probably do the same with my reloads and note any trajectory change. Being a bowhunter, holding slightly high or low on a critter to account for yardage comes pretty easily. A 200yd zero efficiently allows for this.
On longer range rigs where precision factors more into the equation, I have 100yd zero and dial up or use reticle stadia holdover for looong shots. Admittedly, I don't expect to be using these firearms much for predator hunting.
I know that most shots at yotes are well inside of 150 yds, but I feel it wise to cover my butt with a 200 yd zero and be able to hold on fur rather than air in the event a 300 shot presents itself.
If a farther shot is not possible due to terrain/setup, then I'll just hunt with an Aimpoint on that stand.
Same as fishing, efficiently matching the tackle to the species and conditons combined with the knowledge of how to use it yields positive results...