Dave,
If you can give me the muzzle velocity of the load your using, the type of bullet, and its ballistic coefficient, I can plug the numbers into Sierra's Infinity ballistic program, and give you the sight in at 100 yards for a MPBR for the average coyote vital size of 4". That way you can sight the gun in so high at 100 yards and know you will never be more than 2 inches above or below line of sight out to your MPBR. In other words, you could hold dead on out to whatever the software says is your MPBR and still hit the coyote in the kill zone.
Also, if you have a particular distance you would like to zero the gun for I could also use the software to give you the 100 yard sight in to put you dead on at whatever distance you choose.
The software isn't perfect as there are many variables that account for a bullets trajectory, but it will get you real close.
Let me know if you want me to crunch the numbers. It will only take a few minutes.
Mark