The whole deal in using one powder for multiple calibers ends up being a compromise.
IMR 4831 in the 243 and the 75's works ok, same in the 270.
H4831 in the 243 is a tad slow.
I really hate to see a guy go down this road, it is bad thinking all the way around. The next round of bad thinking is that He will only want to buy powders in the one pound cans, one pound at a time unaware that there are lot to lot differences in buring rates.
R#19 is perhaps the best for both the 243 with the 85's and the 270 with the 130's...best compromise. I shoot 45.5g of R#19 with the 85g Tripple shocks with a WLR primer and .050 jump with the 243, worked up a load with the 130g in the 270 but I won't put it in print.
H and IMR 4350 will work well for the 270 with 130g bullests and the 70-100g bullets in a 270, I would work with R#19 first however.