Okay I kinda stirred the pot on this one but I am biased since I own a .20-050 AI. This is an example of " I read it on the internet so it must be true".
A couple of things to think about.
I built my rifle to shoot coyotes.
If I were lucky enough to call in and shoot at 100 plus coyotes a year then in worst case scenario barrel would be gone in 10 years. Pretty cheap if you ask me.
Please look at the ballistics chart below from Berger and see what you think......
Listed first is the .20-250AI with a 55 grain bullet then the .22*250 with a 60
Regards
Bullet Diameter 0.204 inches Zero Range 200 yards
Bullet Weight 55 grains Sight Height 1.50 in
Ballistic Coefficient 0.182 Muzzle Velocity 3610 fps
Temperature 59 F Wind Speed 5.00 mph
Altitude 0 feet Wind Direction 9 o'clock
Inclination 0 degrees Berger Bullets Copyright 2013
Range Card
Range

Velocity
(fps) Energy
(ft-lbs) Elevation
(inches) Windage
(inches) TOF
(s)
100 3329 1353 0.83 0.34 0.09
200 3055 1140 -0.00 1.34 0.18
300 2790 951 -4.58 3.11 0.28
400 2538 787 -13.66 5.76 0.40
500 2298 645 -28.16 9.42 0.52
600 2073 525 -49.30 14.25 0.66
700 1859 422 -78.57 20.44 0.81
800 1657 335 -117.97 28.22 0.98
900 1465 262 -170.12 37.90 1.17
1000 1285 202 -238.58 49.89 1.39
Ballistic Calculator Results
Input Parameters
Bullet Diameter 0.224 inches Zero Range 200 yards
Bullet Weight 60 grains Sight Height 1.50 in
Ballistic Coefficient 0.271 Muzzle Velocity 3700 fps
Temperature 59 F Wind Speed 5.00 mph
Altitude 0 feet Wind Direction 9 o'clock
Inclination 0 degrees Berger Bullets Copyright 2013
Range Card
Range

Velocity
(fps) Energy
(ft-lbs) Elevation
(inches) Windage
(inches) TOF
(s)
100 3286 1439 0.88 0.49 0.09
200 2909 1128 0.00 1.95 0.18
300 2564 876 -5.04 4.54 0.29
400 2245 671 -15.42 8.47 0.42
500 1949 506 -32.80 14.02 0.56
600 1680 376 -59.44 21.55 0.73
700 1442 277 -98.52 31.46 0.92
800 1246 207 -154.48 44.12 1.14
900 1101 162 -232.88 59.66 1.40
1000 1005 135 -339.87 77.74 1.69