This thread is 4.5 years old. But for the sake of conversation, I wouldn't choose either of those bullets for deer. Shooting handgun bullets from a carbine-length barrel can add 400+ fps velocity. That extra velocity can stress the bullet's expansion threshold and cause it to become much more fragile than it was designed to be. As an example, I am working with a new Marlin M1894C .357 magnum with an 18.5" barrel—regular flavor 158 gr. XPTs driven at 1850 fps are fragile and lose their integrity quickly. That means limited penetration and hard bone becomes a challenge. The 158 gr. XTP-FP is designed for the higher velocity of a carbine and expands well but maintains bullet integrity and penetrates much better. Muzzleloader hunters that use sabots and handgun bullets have discovered this also. I had a Hornady 250 gr. XTP turn to shreds inside a whitetail buck hit on the shoulder joint. The bullet was running around 1900 fps from my inline rifle. That bullet was designed for handguns and meant to top out around 1400-1500 fps. I switched to the 300 gr. XTP Mag running at 1800 fps and now get good expansion, bones are no obstacle, and finishes with complete pass-throughs. Hornady has a chart with all the XTP velocity thresholds and is a good guide to choose a bullet from.