My Rem 700 22-250 shoots 40 gr Rem factory ammo with accuracy less that 1 MOA. My father killed a Utah antelope with a single head shot at 325 with one of my 70gr soft point reloads. Twist - 1:14. I shoot 55 gr Ballistic Tips with accuracy consistently .75 MOA or less. I'd say the 1:14 twist is pretty [beeep] versatile - probably why most 22-250 from major manufacturers have a 1:14 twist.