I have them both. The swift is the king of velocity in factory loaded 22 caliber rounds.
The question is "Do you reload"
If not, go with the 22-250. If you reload, the 220 swift will do everything the 250 will do and do it a little faster and a little further. My longest witnessed one shot kill on a coyote was 597 yards. My last 22-250, I had rechambered to AI. It is more accurate than my swift and will run the same speeds. It does this without the stretching that comes with the swift.
I took 4 rifles on the only PD shoot I have ever been on.
17rem, 223, 22-250 and 220 swift. When I really wanted to reach out and touch one in the west Texas winds, the Swift was the round that founds its mark more often than the others.
In factory loaded 22 caliber rounds "When you say swift, you've said it all" (Sung to the tune of the Bud commercial)