Worked for the Air Force at the USAF Marksmanship School, Lackland AFB, San Antonio, TX, and at Kirtland AFB, Albuquerque, NM, in research and development using even bigger "bullets."
Yes, bullets, missles, rockets, etc., do, "go to sleep" at longer than normal ranges. We tested these theories even with electro-magnetic rail guns for super velocities. High speed photography, an extremely difficult process for the velocities we were achieving, showed the results. Very interesting.
On the .243/6mm, we tested these for 1,000yd matches and for reduced recoil in 300meter free-rifle competition. Our initial assumptions from almost 30 years ago were shot down like Snoopy vs the Red Baron. After that, we tested all long range stuff at a minimum of 200yds...and usually at 300yds (it was great at Lackland to have basic trainees as target pullers so we didn't have to continually walk back and forth /ubbthreads/images/graemlins/wink.gif).
Some conclusions for all calibers and match accuracy:
The 6mm Rem gave longer throat life than did the .243 due to length of neck protecting against powder blasting.
Ackley Improved shaped cases with sufficiently longer necks provided the best throat protection.
Bullets of increased length, i.e. VLD, required faster twists, sometimes as much as 1-7, but usually 1-8.
Cleaning effectively and carefully assisted in promoting barrel life.
Barrels could continue with good accuracy by seating bullets out longer and longer until cases couldn't hold the bullet in the proper manner.
Setting barrels back far enough to overcome throat wear and rechambering usually returned the match accuracy, but usually that was gone after about 1500rds. (I used some of the barrels we were discarding for hunting and varminting and had sufficient accuracy for awhile.)
We also tested 6.5-08, 6.5-.284, 6.5 Weatherby/Wright/Hoyer, 6.5-06, 7mm wildcats, and .30 wildcats trying to find out anything we could. Most of this info has been published, but some only in scientific journals.