Yes, and sort-of.
Win 760/H414, is among the older generation of ball powders. It is sensitive to an extent, it isn't as bad as RL-22 in the 25-06, but still somewhat.
The other issue is the 243. As many many reloading manuals/labs have said, the 243 case is a bit of a screwball. The 243 has random pressure excursions, with everything, for no reason.
Starting this summer, and working into this winter I have become a fan of CFE223(SMP-842) for the 243 in a BIG WAY!
Thus far it is incredibly stable, and provides very fast velocities, without pressure issues.