First of all, the 25-06 is a great cartridge in my opinion.
I have a Browning A Bolt that I've had for many years. I found a great bullet for most everything with the Speer 100 gr. SP Boat Tail #1408. That bullet has accounted for five antelope, one of which was at 300 yards, a mule deer, corsican ram, groundhogs and crows. It's very accurate and seems to work well for everything I've used it on.
My load is (use it at your own risk): 54.4 grs of H4831, Remington brass and CCI BR2 primers with the Speer 100 gr. bullet. I generally get 3-shot groups around 1/2" to 5/8", and that being from a slender barrel and a rather stiff trigger. The load is not necessarily a fast one, but it's accurate. That's what matters more to me.
As to performance in the field, most of the antelope I shot with the Speer 100 gr dropped. The 300 yard antelope ran probably 100 yards. It was dead on it's feet, but managed to run a bit. The mule deer dropped on the spot, as did the corsican ram. I did shoot one whitetail deer with the old Barnes X bullet, 100 gr. The deer ran maybe 75 yards and fell. The bullet completely penetrated with a broadside shot. My experience with the X bullets has been limited, but accuracy was not as good as I like.
The Barnes TSX bullets are good ones, very accurate and penetrate into tomorrow. I have used them in three other larger calibers, but not the 25-06. The TSX is a bullet you might want to try, especially if you plan to hunt larger deer, elk etc.