46-H4350 with the 100 Hornady flat base gets me just over 3000 in my Ruger 22" barrel with absolutely no pressure signs. Put one through a mature buck last fall, short ribs on the near side to front of shoulder on the other. As far as I know the bullet is still going. That combo is going to Wyo. this fall for Antelope, along with it's older mate, a M77MKI in .250 Savage
For Coyotes try H4895 with a 75 gr. Sierra. Works great in the 3 .257 Roberts I have tried it in. Just hope you can sew, at 3500+ it's not gonna be too good for pelts.