AA2230 and H335 will give you the best speed with accuracy, and your barrel life should be 6000+ rounds. We learned this on red hot p. dog towns, but we shot a 6x47 Remington with H335, will be hard to wear out a barrel in the 6x45...no kidding.
We shot a lot of H322, but the barrel needs cleaning much more often than with 335 or benchmark. We shot 300 hard and fast rounds inbetween cleanings with the 6x47Remington.
60g Sierra is a whale of a coyote round, and our barrel lengths were 27-28". As soon as the 204 came out, I though this would make one heck of a coyote round with long barrel life with H335 or 2230.