I've shot about 15 coyotes with the 243/75gr Vmax combo so far, and have only had severe pelt damage on one. Ranges were from about 50yds to 430.
It surprised me how pelt friendly the Vmax has been so far. My son had used the 60gr Vmax in his 223wssm @ 3,700fps for 2 years, and he's had some huge splash wounds. Perhaps because of the difference in speeds (the 243 is about 3250fps)?
Both the 243 and the 223wssm shoot the Vmax very, very well.