goose boy:
Lot of love here for the Sierra 40 gr. HP in my 22/250. It is an excellent and accurate bullet; seldom splashes compared to the 40 gr. Vmax, and just penetrates better compared to same.
They do well in a 1X14 and 1x12 twist, and even faster twists will shoot them accurately enough for hunting reliability.
I have used it for over 20 years on small/large OH groundhogs mostly, but there are guys who use them on coyotes with good effect. Work fine for the "closer" shots of up to 200 yards or more.
It is also a comforting bullet to use these around farm buildings etc where ricochet may be an issue (minimizes but does not negate this concern so be safe).
You will like em'; good hunting