I had a 700 VLS a few years back in 22-250 that was a gopher/prairie dog rifle. Thousands upon thousands of rounds through it, and not the slightest loss of accuracy. Held well under 1/2", consistently. Cases lasted forever. It was a flawlessly performing rifle, so I (in my infinite wisdom) sold it. I replaced it with a 700 VSF in the same chambering, and it shoots even better. The name of the game, in my opinion, is not to hot rod it. I shoot 55 grain Ballistic Tips at about 3550 fps. Plenty fast, plenty flat. I never shove more than 50 or so rounds through it before I clean it thoroughly, and am careful to let it cool down, no matter how good the shooting is. I am not sanctimonious about gun care, but the darn things are too spendy to burn out and replace. Even a new pipe is getting up there. I have no experience with, and therefore no opinion on the 20's, but I surely have no complaints with the 22-250. Good luck.