Never hurts to have options. My coyote caliber lineup consists of a 204, 222, 223 (bolt action and AR), 22-250, 243, and 6.8. The 204 is newest and seeing the most use right now. Got its first fur on 1/14/17 and I was highly impressed with the performance. Instant kill and was fur friendly at 34 yards. 222 and 223 work well also. Haven't got a coyote with the 250 or above yet but I'm sure they would do the job admirably and with more authority.