Back when I was a kid my father used to put a sticker on the dash of every vehicle we owned: "Machinery doesn't care".
I'm not finding that I can make a gun like a bullet. I may be able to get acceptable hunting accuracy out of it (say 85 grain Triple Shocks in my .243), but I can't make it produce one ragged hole, or at least haven't stumbled across the sweet spot (yet).
But I have almost given up on bullets using published data only to stumble across a different combination which produces stunning results (58 Vmax in .243 for example).
I loaded up a ton of different 55 grain ammo and my boys and I went out and shot produce and pop cans one day. The 50 grain Nosler ballistic tip is so explosive it is funny, followed by the 55 grain Vmax and then the Sierra 55 Blitz.
But I couldn't for the life of me get groups which made me happy using the Nosler. Heck, out of my .22 PPC Sako it's a spray gun.
I don't exactly like sitting on a partial box of bullets I'll never use, so that's when I try a less popular combination (out of the manuals, I don't truly experiment).
Low and behold I got the Noslers well under 1 MOA out of my middle son's 16" fat barrel AR, so now it's a keeper.
Where it shoots the Nosler, my other son's rifle rings the bell with the 55 Vmax (and factory Hornady 55 Vmax shoots 2+ MOA at best in his rifle).
Now that I reread your post I find that you want to use factory ammo, not a specific bullet. In that case the odds just stacked against you. This my friend, is the real reason many of us hand load. If you're really bent on that particular bullet out of a particular 25-06 you might need to roll up the sleeves and buy a press.
I don't want to be a buzz kill though. Buy a good rifle known for accuracy and give it a shot.