Are you shooting them out of a $3000 dollar rifle, or a $300 dollar rifle? Are you trying to get hunting accuracy, or trying to win a bench rest match?
Totally different answer for each. I think you are over thinking this, and worrying about stuff that advanced reloaders worry about. Ideally you would use cases that have been fired at least once in your chamber for load workup. You would also want to sort through them and separate out any that weren't identical to the others. Weigh them all, check them for capacity, turn necks, trim them all to the exact same length, check them for runout...
Or... load them and call it good. Not every rifle will shoot a one hole group, even with the best reloads. You should get slightly better accuracy from cases that have been fire formed to your chamber. Will you be able to tell it? That will depend on the rifle, and who is pulling the trigger. Honestly, new untouched, chamfered, resized, or once fired, that out of most off the shelf rifles, it would take a lot of testing to tell any difference. Your new brass will have slightly less capacity than once fired, your resizing die will bring them back close to the same size, they will be slightly bigger. Just the way it is. Not worth worrying about.