I have shot 58 grain VMax, 65 grain Bergers, 70 grain Sierra HP's, and 85 grain Sierra HP's in various 243's with extremely good results, using W760 powder in all of them. My powder charges have all been on the high side with no signs whatsoever of being too hot. I have also tried 90 grain Noslers, 95 Grain Hornday SST's, and 100 grain Remingtons trying to come up with a deer load that shoots as well as the lighter weight bullets, but have had mixed results, using several different powders. If I had to pick one bullet and powder it would be the Sierra 85 grain HPBT and W760 powder. This load has shot good in every 243 I've tried it in.