I would use lead Hornady V-Max bullets or the Hornady 35 gr NTX Lead Free bullets before I would use Barnes Varmint Grenade bullets.
I have never seen a 35 gr Honady NTX Lead Free bullet at 3800 fps and faster leave a exit hole in a coyote.
Many years ago my son was shooting ground squirrels with Hornady 35 gr NTX 223 Rem Superformance factory loads at 4000 fps. Those 35 gr NTX bullets were launching and flipping ground squirrels farther than I had ever seen before.