They simply don't work worth a darn. Lots of runoffs. This was supposed to be the cure for hide damage but it's not. Stay with jacketed bullets.
I tried these for about six months years ago when coyote hide prices were pretty good in my 22-250. Thought I'd save the pelt sewing damage that regular 22=250 loads do. First six yotes shot three ran off and after two and a half hours of tracking I finally gave up. Better to shoot a fur friendly gun such as the 17 Rem or the 204 if your planning on harvesting.