I would suggest that you read the article in Predator Extreame that talks to those "very well known pros" and what you see is that most of them use Vmax.
These guys kill a lot of coyotes. Vmax works well.
I used the 40gr in my 22-250 [1:14 twist] it stabilized very well and I had great results.. I shot several fox, bobcat, and more than a truck load of coyotes. I didn't have anymore blowouts than anything else i have tried. That isn't the bullet but the energy of the bullet and the bones. I had fox that had pin pricks, and most coyotes i had to drag to the truck before a drop of blood came out to show where the bullet impacted. Yes, i have had some that needed sewing, but so what. 10 minutes of sewing, is a lot better than spending time (limited as it is) when i am hunting looking for a dead coyote. I have never had a coyote make it more than 20yrds. I had nothing but tracking issues with HPs and others like SPs. I did have a blowout of a Lynx that left me in tears when the bullet blew out the backside of the lynx at 45yrds, but that is the reason I carry a shotgun. I use that for everything inside 40 yrds and use the rifle for everything else. Now i only get a few a year that have to be sewn.
The round doesn't expand until after it goes in. If you hit a bone, most are going to cause you to sew. I don't like to and do what i can to wait for a broadside shot. If i do shoot a head on shot, I aim for just below the back bone level. Any lower and the shot will be between the armpits and that doesn't make skinning easier, it makes for a mess. That and head shots. The only time i do that is with the shotgun. Rifle bullets in the head make skinning and fleshing take more time and costs me money becuase of the time it takes to skin and then flesh.
This kind of question comes up almost monthly.
I know few people on here that actually skin, stretch, flesh, or sew. So i am not sure why "splash matters" I would rather spend 10 minutes sewing than 30 minutes looking for a dead coyote. once i stopped shooting coyotes the way you would shoot a deer, the splash wounds almost stopped. I know when it's going to happen when i shoot and hit the bones in the ribs in a head on shot, or shoulder shot. I now aim for mid body of a little high of center broadside shot. I aim for just after the last rib. Why? Because when you hit there that vmax goes in, and doesn't hit a bone, and then expands and the inside is just jello. They drop DRT and in some cases they even leave a face print in the dirt or snow. Dead as a stone.
If i was going to work up a load, i would suggest that you look at 40-53gr bullets. I think the 53 is a far superior round, and if your rifle likes it, would use that over anything else. Of course the most accurate should win.