no offense to you guys, but i am guessing that most of the previous posts are posted without actual experience. just like the people who ask me about shooting my antelope with a 50, i get asked "was there anything left", or "did it cut it in half" and other things along those lines.
i have personally shot several coyotes and a few fox with my 270 using the same loads i use for deer. a fox is about as light a creature as it gets, the bullet goes in, the bullet goes out the same size. i have not had a bad experience with it yet.
i have shot coyotes with 270, 243, 223, 223 wssm, 22-250, 45 win mag, 22lr, 308, and maybe some others. i have had major hide damage with 223, 223 wssm, 243, 22-250, and 308. i have shot more with the 223 than all others, but even with a 223 i have blown up bobcats and fox. a poor shot angle, wrong bullet, or hitting major bone can ruin a hide regardless of what you are shooting.