Soreloser, from the comment below, I think that your expectations of what misting does is incorrect, so let me clarify.
"And by work I'm mean holds them down wind for a unknown period of time instead of running for safety. Much like not using the misting technique, sometime a coyote will stay downwind and not care, more often they run like the devil.
What I really want to see is comprehensive study of how many coyotes come in down wind and how many stick around because of misting and how many stick around while not misting. Since I do not mist I will keep track of the NON-Misting downwinders during my season this year if you or Rich will keep track of the misters."
Misting is an attractant that confuses the nose/brain. I have used rabbit urine, sardines, and fish oil. It works as an attractant, and when used on a drag, will get them to follow a predicted path to you when they cross your trail.
Misting is not to be confused with cover scent which eats human bacteria which causes us to stink. Misting will also not cover the scent on the bottom of your boots that you picked up at the gas station "filling up".
When doing so much hunting at night, it never ceased to amaze me at how many yotes circle down wind 300-250 yards out. The 2 yr old yotes want to smell who is up wind, both prey and friend. Some of those fellow yotes are not friendly at all with sharing the groceries with another family member must less with another coyote that is not of their territory.
When we were hunting in Mexico, it amazed me at how many coyotes would always run with their noses in the wind. They want to smell their prey in front of them, and or a larger more dominant coyote.
I, my brother's, and many others have been very successful in trying a cover scent called Forget the Wind. When used properly, it dilutes the human scent so that the parts per million of human order that the coyote picks up is much less than the more powerful Attractant that is used. The attractant simply over powers the nose. Even when not used with an attractant, it is obvious that they don't spook when they cross your trail, which is simply unreal to witness time and time again without fail.
Don't even think of comparing a blood hound's trained nose to a wild coyote...apples and oranges.
The trappers that read this post will laugh their butts off at how some hunters just don't believe that attractants work. Heck, the trappers would never catch anything in their foot hold traps with out some kind of attractant!
So, if you want to increase your odds, use a cover scent and/or an attractant. If you don't want to fool around with them, it's your hobby...take it as serious as you feel necessary to give you self gratification.
In every hobby, you have the personality types that are real serious, and others that are in it just for the fun.
No doubt that when a guy is fortunate enough to live in areas that have high populations of coyotes, his chances of success are much higher without using anything.