I shot the 50g Nosler at 4200 out of a 27" long Hart 14" twist barrel 22/250 AI. Groups were in the 1/4" area or smaller, three shot groups, Win 760 and Federal primers.
Coyotes died without suffering, real quick. No surface explosions.
We also shot several hundred with the 50g Sierra Spt, excellent accuracy as you would expect from Sierra with great results on coyotes.
If you want to see a real mess of a coyote, then try the 55g Sierra Blitz lead tip, amazing accuracy out of this bullet also. Rough barrels and 7" T twists may spin apart the lead tip blitz. 9T out of a 223 Ar would be a great platform for the 55g lead tip Blitz,26.0- 26.5g of Win 748.