I think each manufacturer's offerings come with some advantages and disadvantages inherent to each design. It has long been known that the Ruger Blackhawk and Super Redhawk .44 magnum revolvers are more robust than the N frame Smith & Wesson revolvers. It has also been well known for many years that the S&W design offers a superior out of the box trigger, and is a bit more refined revolver.
If your desire is to shoot a steady diet of heavy 300 grain bullets at maximum velocity, you may want to get yourself a Ruger Super Redhawk. If you intend to shoot standard .44 Magnum 240 grain bullets at standard .44 Magnum velocities, a S&W model 29 or 629 will serve you very well.
Some also prefer the recoil impulse from the SA design of the Ruger Blackhawk, while others prefer the feel of the DA S&W design.
I currently personally own two .44 Magnum revolvers. A 4 inch 29-2 I bought new in 1978, and a 6.5 inch 6-29 Classic I bought used in 1987 or so. I use the 29 as my woods carry gun during firearms deer season, and have used it to take a few deer. I use the 6.5 6-29 in the same way during foul weather. It's also taken a few deer, including my first ever handgun buck shortly after it became legal to hunt deer with handguns in Indiana. When I began using my .44 magnums for deer, I found Winchester Supreme 250 grain partition golds worked very well. I'm down to about a dozen rounds of that ammo left, and can't find the partition bullets as components, so I now shoot 240 grain Hornady XTP's over 20 grains of 2400 from both revolvers and my Marlin 1894. These loads are great deer killers. I've recovered every deer I've ever shot with them in less than 75 yards.