My snare of choice is 7x7 3/32 cable with a 1/8 cam lock. I am still using several 3/32 cam locks that I started out with, but I have found that the larger locks function better in wet and freezing weather. Another factor is what your target animal is. I am only making land sets, targeting the canines and cats, with the occasional coon that gets caught up. If I was primarily targeting coons, I would probably try 5/64 with a 3/32 cam lock. I have never used this combo, but it is what I would use if I set any number coon snares. Also, I have never made any water sets so I don't know what would be best for say beaver or mink.