I'm not running the 25-06 fan club here esp. since I've never shot one (Internet Gun Expert!)...I will say that out here in Northern California where a big blacktail buck will only weight 175 pounds and most run a lot closer to 100, that a lot of guys go with the 25-06.
It throws that 120 bullet that is great for side to side shots across draws and small canyons out to 300 or even 350 yards....I always thought of it as a 243 on steroids, but alas when it was time for me to abandon the trusty 243 of my youth, I skipped right over the 26-06 and went for the 7 mag....When you're 16 you're sure that by the time you are 21 you'll be hunting buggling elk every fall (so you might as well buy the rifle for it now)...Well I've yet to shoot an elk buggling or otherwise, but I've killed a lot of blacktails with the big 7....They're dead and eaten, but I think they would have been just as dead with either a 308 or a 243...or even that worthless old 25-06....lol